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wholesale Ondansetron(HCL)99%
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Molecular Formula: C18H20ClN3O
MOQ: 1kg
Content: 99%
CAS Number: 99614-02-5
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1.00kg 24.00kg USD818.97  /kg
25.00kg 1000.00kg USD754.31  /kg
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Specification

Molecular Formula C18H20ClN3O
MOQ 1kg
Content 99%
CAS Number 99614-02-5
Molecular Weight 329.82
Ondansetron(HCL)99% Detail

Ondansetron Basic information
Product Name: Ondansetron
Synonyms: 1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1h-imidazol-1-yl)methyl)-4h-carbazo;gr38032;gr38032x;GR 38032F;ONDANSETRONE HYDROCHLORIDE;ONDANSETRON HCL;ONDANSETRON HCL DIHYDRATE;ONDANSETRON HYDROCHLORIDE DIHYDRATE
CAS: 99614-02-5
MF: C18H20ClN3O
MW: 329.82

Product Categories: Active Pharmaceutical Ingredients;Ondansetron;Serotonin

Ondansetron lowers the cravings for alcohol, especially in early-onset alcoholics. In one cognitive-behavioral therapy study, ondansetron patients with early-onset alcoholism had fewer drinks per day and reported more days without drinking at all, as compared to the other groups in the study. 

Also of note, individuals with the LL genotype show significant improvements in alcohol misuse when treated with ondansetron,

 compared with individuals with the other genotypes of the 5HTTLPR polymorphism, who showed no improvement over placebo.
Researchers at the Stanford University School of Medicine have demonstrated that ondansetron might be useful and effective

 for treating withdrawal symptoms of opioid addictions. Unlike the existing treatments methadone and buprenorphine, it is not itself an opioid. Additionally, it does not require continued supervision like treatment with clonidine.
The original experiment used mice who were injected with increasing doses of morphine, assayed with naloxone and then underwent haplotypic analysis to isolate a gene candidate.HTR3A which codes for the 5-HT3 receptor emerged as the primary candidate, which suggested 5-HT3 antagonist ondansetron as a possible treatment. The researchers were then able to show using an acute morphine administration model the efficacy in withdrawal symptom control in humans


 

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Related Searches
tetrahydro    alcoholism    re    Poly    chlor    c18    effect    medicine    CAS    Ondansetron    99614-02-5    1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1h-imidaz    gr38032    gr38032x    GR 38032F    ONDANSETRONE HYDROCHLORIDE    ONDANSETRON HCL    ONDANSETRON HCL DIHYDRATE    ONDANSETRON HYDROCHL    
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