Dihydroartemisinin
CAS: 71939-50-9
Molecular formula: C15H24O5
Specifications: CP2005 HPLC
Dihydroartemisinin:
1)white needlelike crystal
2)Antimalarial
Dihydroartemisinin chemical designation is (3R,5aS,6R,8aS,9R,12S,12aR)- octahydro-3,6,9-trimethyl-3,
12-epoxy- 12H-pyrano[4.3-j]-1,2-benzodioxepin-10(3H)-one. Malaria is one of leading re-emerging infectious disease due to murative malarial parasite developed resistance to chloroquine. Sulfadoxine-pyrimethamine is an alternative can be used in the treatment of the disease resistant to chloroquine,
but resistance to sulfadoxine-pyrimethamine has been reported also in some areas. Artemisinin is an alternative
used in areas where the disease has become highly resistant to sulfadoxine pyrimethamine. Dihydroartemisinin,
its methyl ether (artemether), its ehyl ether (its (arteether) and its hemisuccinate ester (artesunate) are known as more effective than
its parent material - artemisinin.
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