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You are here: Home >Extracts> Herbal & Plant Extracts > alpha arbutin(99%)
wholesale alpha arbutin(99%)
FOB Price:USD993.10/kg
Quantity:  kg
Minimum Order Quantity: 1kg
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Appearance: White fine powder
Sources: Bearberry
CAS Number: 84380-01-8
MOQ: 1kg
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Start Weight End Weight Price
-- -- USD993.10  /kg
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Specification

Appearance White fine powder
Sources Bearberry
CAS Number 84380-01-8
MOQ 1kg
Specification 99%
Molecular Formula C12H16O7
Molecular Weight 272.25
Loss On Drying 1% Max
Sulphate Ash 1% Max
Heavy Metal 10 ppm
E.Coli Negative
Salmonella Negative
Bioactive Ingredients α-Arbutin
Purity 99%
Package 1kg/bag,25kg/fiber drum
Mesh 80 mesh
Standard Enterprise Standard
alpha arbutin(99%) Detail

[Product name]: α-Arbutin

[Botanical Source]:  It is the discolored parts of natural green plant (such as, bearberry’s leaves, Pyrus pyrifolia ’s leaves, Saxifraga stolonifera Meerb and so on ).
[Quality standard]:
1. Active Ingredient: alpha-Arbutin              
2. Part used: Leaf
3. Appearance: White fine powder
4. Mesh: 100% pass 80 mesh 
5. Odor: Characteristic
6. Loss On Drying: 1%
7. Sulphated Ash: 1%
8. Heavy metal: 10PPM
9. Residual Solvents: 0.05PPM
[Microbiology standard]
1.Total Plate Count: 1000CFU/gm
2.Yeast&Mold: 100CFU/gm       
3.Salmonella: Negative     
4.E.Coli: Negative  

[Pharmacological Function]: Whitening and dispelling fleck, preventing ultraviolet radiation. Enhancing our immunity; It is good for our enteric disease. It has antiphlogistic and analgesic function to burn and scald. 

Arbutin exerted its effect through a controlled release of hydroquinone by the in vivo hydrolysis of the glycosidic bond. It is reported by various researchers to inhibit the oxidation of L-DOPA catalysed by mushroom tyrosinase. A recent study indicated that arbutin inhibits melanin synthesis by inhibition of tyrosinase activity. This appears to be due to the inhibition of melanosomal tyrosinase activity and Pmel-17 protein at noncytotoxic concentrations rather than the suppression of this enzyme’s synthesis and expression. It also inhibits the maturation of melanosomes, possibly by its reported influence on DHICA (5,6-dihydroxyindole-2-carboxylic acid) polymerase activity. It is thought that the activity of arbutin is driven by the structural homologies that it shares with the substrate tyrosine. It was showed that arbutin inhibits the oxidation of L-tyrosine (monophenolase activity) catalysed by mushroom tyrosinase and that it competes for active binding sites in tyrosinase without influencing the mRNA transcription of tyrosinase or being oxidized.  However, arbutin itself was oxidized as a monophenol substrate at an extremely slow rate, and the oxidation was accelerated as soon as catalytic amounts (0.01 mM) of l-3,4- dihydroxyphenylalanine (L-DOPA) became available as a cofactor.

[Package]:
Double plastic-bag inside, aluminum foil bag paper or fiber drum outside. N.W:25kg/drum
[Storage]: Store in cool and dry place and avoid light and heat.

[Shelf Life]: 2 years


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