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Hydroxybutyl-β-cyclodextrin
Abbreviate: HB-β-CD
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Compound
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R1
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R2
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R3
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2-O-hydroxybutyl-β-CD
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2-hydroxybutyl
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H
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H
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6-O-hydroxybutyl-β-CD
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H
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H
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2-hydroxybutyl
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2,3,6-tri-O-hydroxybutyl-β-CD
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2-hydroxybutyl
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2-hydroxybutyl
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2-hydroxybutyl
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Applications:
Hydroxybutyl-β-cyclodextrin (HB-β-CD) is a new cyclodextrin derivative.
1. In pharmaceuticals industry, can increase solubility and bioavailability of drugs, so that the efficacy of drugs can last longer with less ingestion of drugs. It can adjust and control drugs release ratio, decrease side effects of drugs, and enhance stability of drugs.
2. In food and perfume industry, HB-β-CD can enhance the stability of nutritional constituent and extend active time of effective constituent. It can cover up bad smell and bad taste of nutritional constituent.
3. In cosmetics industry, HB-β-CD can reduce stimulate of organic molecular in cosmetic to the skin and mucosa. It can enhance the stability of matter, by preventing oxidation and volatilization of nutrients.
4. In chiral separation, HB-β-CD shows excellent performance in the latest study.
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