| The product is an excellent enteric film coating material. Mainly used as tablets, granules etc. The enteric coating material gentle release reinforcing material, enteric-coated capsules and microencapsulation matrix adhesives, implants, gradient release system, taste masking agents, microspheres, oral membrane , such as preparation of solid dispersions, the release rate and the PH value of the related. Technical specification:
Comply with USP and EP.
| Item |
Grade |
| HP55 |
HP55S |
| Methoxy (WT%) |
18.0-22.0 |
18.0-22.0 |
| Hydroxypropoxy (WT%) |
5.0-9.0 |
5.0-9.0 |
| Phthaloyl group (WT%) |
27.0-35.0 |
27.0-35.0 |
| Viscosity (mPa.s) (10% solu., 20±0.1℃) |
32-48 |
136-204 |
| Loss on drying (%) |
≤5.0 |
≤5.0 |
| Residue on ignition (%) |
≤0.20 |
≤0.20 |
| Chloride (%) |
≤0.07 |
≤0.07 |
| Heavy metals (ppm) |
≤10 |
≤10 |
Preparation of coating solution:
1）Concentration of coating solution
| Item |
Tablet |
Granule |
| HP55 |
6-10% |
5-7% |
| HP55S |
5-8% |
4-6% |
2）Organic solvents for HP
Acetone: Water =9:1
Methylene chloride: Ethanol =1:1
Acetone: Ethanol = 1:1
Ethanol: Water = 8:2 (Solution temperature above 25℃)
Methylene chloride: Ethanol: Water = 5:4:1
3）Dissolving method
Added to the container a certain amount of solvent, under stirring, slowly add HPMCP stir until fully formed viscosity.
4）HPMCP usage is generally 6-10% the amount of core chip.
Package:
12.5kg / fiber drum (20 feet container can load 4.5MT with palletized and 5MT without palletized; Packing size: H500mm x D380mm) |
