Cantharidin

CAS: 56-25-7
MF: C10H12O4
MW: 196.2
EINECS: 200-263-3
Product Categories: chiral
mp  215-217 °C(lit.)
Chemical Properties： white to light yellow crystal powde
General Description ：Brown to black powder or plates or scales. Formerly used as a counterirritant and vesicant. Used for the removal of warts. Used as an experimental anti tumor agent. Active ingredient in spanish fly, a reputed aphrodisiac.
Reactivity Profile： Organic anhydrides, such as Cantharidin, are incompatible with acids, strong oxidizing agents, alcohols, amines, and bases.
Health Hazard： Cantharidin is classified as super toxic. Probable oral lethal dose in humans is less than 5 mg/kg or a taste of less than 7 drops for a 70 kg (150 lb.) person. It is very toxic by absorption through skin.
Fire Hazard： When heated to decomposition Cantharidin emits acrid smoke and irritating fumes.
Biological Activity ：Natural toxin inhibitor of protein phosphatases 1 and 2A (K i values are 1.1 and 0.19 μ M respectively); similar to okadaic acid (9,10-Deepithio-9,10-didehydroacanthifolicin ). Displays > 500-fold selectivity over PP2B.