Usage:A dihydropyridine calcium channel blocker. Used as an antianginal and antihypertensive
Biological Activity:L-type calcium channel blocker that displays antihypertensive properties. Inhibits Ca 2+ -induced contractions in depolarized rat aorta (IC 50 = 1.9 nM) and displays vasoprotective effects in
cardiovascular disease. Inhibits proliferation of human vascular smooth muscle cells and epidermoid
carcinoma A431 cells (IC 50 = 25 μ M).
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